How to Interpret a COA (Certificate of Analysis)
How to Interpret a Peptide COA: A Guide to HPLC and Mass Spectrometry Certificates of Analysis (COAs) are frequently cited in peptide research, yet they are often misunderstood or oversimplified. Many vendors highlight a single purity percentage without explaining how it was measured, which techniques were used, or what that number actually represents. This overview focuses on the analytical techniques that give a COA real value: High-Performance Liquid Chromatography (HPLC) for purity…
